This medicine contains the active ingredient spironolactone which belongs to a group of medicines called diuretics, also known as water tablets. These medicines cause the kidneys to produce more urine, and in that way they free your body from retaining the amounts of water higher than needed. Spironolactone is prescribed for the treatment of ascites and edema (water retention caused by heart failure, liver disease (cirrhosis) or malignant disease), hypertension (high blood pressure), diagnosis and treatment of a primary aldosteronism (excessive production of aldosterone, a steroid produced by the adrenal gland).
Is Spironolactone suitable for me?
Spironolactone is not suitable for everyone. Do not use it
- if you are allergic to spironolactone or to other ingredients of this medicine
- if you have diabetes mellitus
- if you have kidney problems
- if you are not passing any water
- if you are breast-feeding
- if you have hyperkalaemia (raised blood potassium levels)
- if you have an illness called ‘Addison's Disease’
In particular, you must tell the doctor if you:
o have changed levels of potassium or sodium
o have liver cirrhosis
o have diabetes
o suffer from serious respiratory disorders
o suffer from diarrhea
o have recently had surgery or you are seriously ill
o have abnormal periods or swollen breasts
o have porphyria (blood disorder)
o are pregnant or breast-feeding
o are elderly
Spironolactone interacts with other medicines. It is most important that you tell the doctor all the medications and herbal supplements that you are currently taking.
See the package leaflet for a complete list of possible contraindications and warnings.
How should I take Spironolactone?
This medicine is available in form of a film-coated tablet.
You should take spironolactone exactly as instructed by your doctor or pharmacist.
- The usual dose is between 100 and 400 mg per day.
Do not use more of it, do not use it more often, or do not use it for a longer time than your doctor instructed. Also, this medicine works best if there is steady amount in the blood. To help keep this amount constant, do not miss any doses and take the medicine at the same time each day. Do not take two doses together if you miss a dose.
Read the information leaflet provided with your medication for additional information. Talk to your doctor if you have any additional questions.
What are Spironolactone side effects?
Like all medicines spironolactone can cause side effects, including:
- nausea, stomach upset
- confusion, dizziness
- menstrual problems in women
- change in sex drive for both men and women
- disturbances in body electrolytes
- reduced number of cells that fight infection - white cells (leukopenia)
- reduced number of cells that help with clotting (thrombocytopenia)
- excessive growth of breast tissue in men (gynaecomastia)
- breast lumps, breast pain
- skin rash, itchiness
- excessive hair growth (hypertrichosis)
- skin condition presenting with fluid-filled blisters (pemphigoid)
- hair loss
- general weakness, muscle cramps
- sudden kidney failure
Consult a doctor if the side effects are severe. See the package leaflet for a complete list of side effects.