NEO-PENOTRAN

This medicine contains two active ingredients, 750 mg of metronidazole and 200 mg of miconazole nitrate. Metronidazole belongs to a group of medicines called antiprotozoal and antibacterial agents. Metronidazole is very effective in the treatment of bacterial vaginosis (bacterial infections of the vagina caused by increase in the amount of naturally present bacteria). Miconazole is an imidazole antifungal agent, which is used for the treatment of fungal infections, as well as for the treatment of some bacterial infections. Neo-Penotran Forte is prescribed for the treatment of candidal vulvovaginitis due to Candida albicans, in bacterial vaginitis due to anaerobic bacteria and Gardnerella vaginalis, in trichomonal vaginitis due to Trichomonas vaginalis and in mixed vaginal infections.

Is Neo-Penotran Forte suitable for me?

Neo-Penotran Forte is not suitable for everyone. Do not use it

• if you are allergic to metronidazole, miconazole nitrate or to other ingredients of this medicine
• if you are drinking alcohol
• if you are using disulfiram
• if you are in the first trimester of pregnancy
• if you have porphyria, epilepsy and severe liver disorders

In particular, you must tell the doctor if you:

• have liver damage
• have hematological disorders
• have cardiac rhythm disorders
• have difficulty in breathing
• are pregnant or breastfeeding

Neo-Penotran Forte interacts with other medicines. It is most important that you tell the doctor all the medications and herbal supplements that you are currently taking.

See the package leaflet for a complete list of possible contraindications and warnings.

How should I take Neo-Penotran Forte?

This medicine is available in form of a pessary.

You should take Neo-Penotran Forte exactly as instructed by your doctor or pharmacist.

• The usual dose is one pessary per day (inserted into the vagina at night).

Do not use more of it, do not use it more often, or do not use it for a longer time than your doctor instructed. Do not miss any doses and use the medicine at the same time each day. Do not apply two doses together if you miss a dose.

Read the information leaflet provided with your medication for additional information. Talk to your doctor if you have any additional questions.

What are Neo-Penotran Forte side effects?

Like all medicines Neo-Penotran Forte can cause side effects, including:

Very common:

• vaginal discharge

Common:

• vertigo
• headache
• vaginitis
• vulvovaginal irritation
• pelvic inconvenience

Uncommon:

• depression
• thirst

 Very rare:

• allergic reactions
• mental changes
• vaginal burning
• itching and irritation
• abdominal pain
• skin rash

Consult a doctor if the side effects are severe. See the package leaflet for a complete list of side effects.